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[DOI] [Google Scholar] Failla M., Floresta G., Abbate V

Ive had two [patients] come in that are ready for surgery recently that have experienced GI bleeding, Sadler says

For both, the cause is connected to alterations of the functionality of the relative enzymes, such as succinate dehydrogenase (SDH) and fumarate hydratase (FH), respectively, that include loss-of-function mutations, transcript degradation by miRNAs, post-translational modifications, and protein degradation

Without enough glutathione, NAPQI builds up and can damage liver cells

Impact on Daily Life Although NSCP is not a serious medical problem, it can still affect everyday life