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Hence, it can be seen that many environmental pollutants are capable of inducing eryptosis in human RBCs, and that eryptosis may be an effective indicator for comparing the hematotoxicity of parent compounds and their metabolites [423], to assess the toxicity of their potential replacements [421, 422, 428], and to investigate the mechanisms of action of toxic metals [184, 420, 424, 435] and pesticides [436, 437]

However, for some individuals with residual absorption capabilities, high-dose oral supplements can serve as an alternative

nausea and vomiting

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Collectively, these findings demonstrate that polyphenols and flavonoids act through a synergistic multi-target mode of action anti-inflammatory + antioxidant + anti-apoptoticwhich is more suitable for addressing the complex pathological processes of chronic inflammation compared to conventional single-target drugs