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Additionally, a preclinical study using a rabbit TB model showed that bevacizumab inhibited neovascularization, enhanced drug penetration into granulomas, improved lung pathology, and increased oxygenation, suggesting its potential to enhance the effectiveness of the current TB regimens [37]

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Although it has been hypothesized that fluoxetine may interfere with spermatogenesis by affecting androgen levels, the concentrations of gonadotropins such as FSH and LH levels were not quantified in the study, and the underlying mechanism of action could not be directly confirmed

Surgical management of endometriosis-related infertility does improve pregnancy rates, but the magnitude of improvement is unclear

Consistent with its proposed role in long-distance transport, OPT6 is highly expressed in the vasculature [161]