The pills havent been compared head-to-head in a clinical trial, but in separate studies, the Wegovy pill showed average weight loss of 14% over 64 weeks, compared with 2% for a placebo, while orforglipron showed 11% weight loss over 72 weeks on its highest dose, compared with 2% for the placebo group
Rough monthly math: protein powder $2540, creatine monohydrate $1015, magnesium glycinate $1020, a tested-deficiency vitamin $1020
These populations already face elevated bone loss risk, and adding GLP-1 therapy without calcium and vitamin D supplementation multiplies that risk substantially
And their lives
Standard daily dosing protocol Most compounding pharmacies and prescribing providers recommend once-daily dosing for sublingual GLP-1 drops
Some describe microdosing as helpful during transitions, such as restarting after a break or adjusting due to side effects