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95 Furthermore, other literature suggests that JS-K inhibits angiogenesis, 96 induces cell apoptosis (a process related to PARP, caspase 8 and 9 cleavage, and cell differentiation), 95,97 destroys double-stranded DNA, 95,9799 and is also able to interfere with the cell cycle and its respective signaling pathways

PMC 10883097

This chapter the role of redox state in apoptosis perturbation, exploring how the imbalance in redox status not only can directly responsible for tissue damage, but also promote development through the imbalance of immunological tolerance and the generation of neo-antigenic determinants from one side and of autoantibodies from the other