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Gastrointestinal adverse events were reported in 62% of the group taking semaglutide, compared to 42% in the placebo group.[ref] Bigger picture of GLP-1 in the rise of obesity: Several recent studies shed light on how environmental factors may be causing a decrease in GLP-1 levels
Instead, researchers track overall weight loss, fat mass reduction, and body composition changes
Recent studies published in 2024 show an increased risk of NAION, particularly in patients using these drugs for weight loss
Galloway et al., 2011 L-
Splitting the dose or adding a second daily injection is not part of the clinical protocol and may not improve outcomes
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