Iron overload was thought to play an important contributory role in shaping the EMs inflammatory microenvironment and cell adhesion [6, 15, 27]
The oncometabolite D-2HG produced in IDH-mutant tumors from KG contributes to inhibiting antitumor immunity via the metabolic reprogramming of CD8+ T cells and decreasing their proliferation and antitumor toxicity [100]
Mecanismo A literatura descreve dois mecanismos interconectados
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