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In response to comments from interested parties, we agreed that, given the limited claims data available and a new outpatient indication for C2645, a payment rate for HCPCS code C2645 based on the geometric mean cost of $1.02 per mm 2 may not adequately reflect the cost of HCPCS code C2645

These results highlight a close relationship between oxidative stress and cellular functions

Individual factors like age, weight, and baseline IGF-1 guide dose adjustments

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