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It wrings out the excess fluid, but it doesn't touch the underlying fat stores

Cftr potentiators: From bench to bedside

Edison P et al

doi: 10.1016/j.biochi.2019.02.003 33 HallA

Moreover, the upregulation of LDLR gene expression in cells treated with GLP-1RAs occurs through both SREBP-2-dependent and SREBP-2-independent pathways