For a population of people with type 2 diabetes and first-time GLP-1 RA prescriptions, we found decreases in baseline A1C and BMI values (prior to GLP-1 RA initiation) between January 2020 and November 2023
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At the same time, it has been hypothesized that autophagy pathways involved in lysophagy in non-erythroid cells, e.g., the p62-mediated pathway [67], might be responsible for the clearance of lysosomes in the erythroid lineage as well [51]
The issue is that the Vyvanse seems better at improving movement and irritability but the Concerta seems better at the so-called 'Executive Functions' of the prefrontal cortex
As activated microglia attempt to clear S aggregates, this leads to the release of proinflammatory mediators and ultimately neurotoxicity (Hoenen et al., 2016)
