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(2012) 129:68793.e1
At a genetic level it has the potential to alter an individuals capacity to build superior muscle density and size
Taken together the anti-cancer effect of biguanides is being studied in several types of cancer suggesting the potential repurpositioning not only of the anti-diabetics, but also of numerous other biguanides-related compounds
Custom pathways used for gene set analysis are described in detail in Methods Details below
Microglia, the primary immune responders in the brain, release proinflammatory cytokines when activated, which then stimulate nearby reactive astrocytes, amplifying local neuroinflammation
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