Direct human dose-finding trials are limited
FDA Statement This product is not evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease
Uh, and I also think that in terms of healthcare, I tend to look at the basics first, right
In contrast, there is some evidence of an enhancement of the maximum absorption via intrinsic factor, by up to a factor of 2, when the vitamin B12 is accompanied by food, but this is not consistently observed and probably only applies when the food quantity and vitamin B12 dose are sufficient to slow the passage of the vitamin B12 through the small intestine enough (about three hours or more) to allow each intrinsic factor receptor to absorb two molecules of vitamin B12 from the oral dose rather than one
These findings have implications for stroke rehabilitation research, traumatic brain injury recovery, and potentially neurodegenerative disease treatment approaches
132 , e148546 (2022)