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Granulation tissue formation accelerates, and re-epithelialization begins in earnest for wounds healing by secondary intention

Cells were cultured and treated in a 37 C humidified incubator gassed with 5% CO 2 and 90% N 2 so as to achieve bone marrow level hypoxia of 5% O 2 or alternatively room air without N 2 to achieve 20% O 2

The same trial found no serious adverse effects, no liver toxicity, and no kidney problems

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