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Effect of selenium status on thyroid disease Selenium deficiency has been associated with a number of adverse thyroid conditions, including hypothyroidism, subclinical hypothyroidism, enlarged thyroid ( Reference Derumeaux, Valeix and Castetbon 74 Reference Rayman, Duntas, Luster, Duntas and Wartofsky 77 ) , thyroid cancer ( Reference Schmutzler, Mentrup and Schomburg 67 , Reference Rayman, Duntas, Luster, Duntas and Wartofsky 77 Reference Lin, Kuo and Chiang 79 ) and AITD, including HT ( Reference Wu, Rayman and Lv 75 , Reference Rayman, Duntas, Luster, Duntas and Wartofsky 77 ) and GD ( Reference Rayman, Duntas, Luster, Duntas and Wartofsky 77 , Reference Bulow Pedersen, Knudsen and Carle 80 )

Trained assessors administered the battery of assessments, 8 different tests in total, over a consecutive two-day period

2024 Jan;50(1):1-16

Additionally, further studies are needed to explore the interplay between necroptosis and other types of cell death

Patients should undergo a comprehensive evaluation to identify the etiology of WR, after which a targeted and personalized intervention should be performed for each patient

Maintenance protocols typically use lower doses than initial loading phases