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Cagrilintide has been studied in combination with semaglutide as a fixed-dose therapy, with promising results: the combination amplified weight loss compared to semaglutide alone, while preserving lean mass better than monotherapy

There was also a possible trend of an increase in triglycerides (+47%, p = 0.06) - initially all were normal, and at the end of the study 2/21 were elevated

Its dual-action profile makes it especially relevant for studies analysing synergistic peptide interactions and integrated regenerative signalling models

ROS and the DNA damage response in cancer