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Asymptomatic patients who ingest more than 20 mg/kg of elemental iron but are seen within 6 hours might benefit from gastric lavage with saline

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Andrologia 53, e14062

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Tirzepatide's simultaneous GIPR and GLP-1R engagement generates two spatially distinct cAMP pools that converge on EPAC2, producing a larger net insulin secretory response than single-receptor stimulation at equivalent total cAMP levels [18]