Long-term safety of spironolactone in acne: results of an 8-year followup study
The additive effect validates the biological hypothesis: amylin and GLP-1 engage overlapping but distinct neural circuits, and activating both produces a synergistic response that neither achieves independently
Easier access to effective pharmacotherapy could help patients with obesity reduce upper airway collapsibility and metabolic comorbidities
When access is dictated by price rather than choice, that fear is compounded by injustice
To move to an earlier day in the week, take your next dose on the new day (creating a one-time 6-day interval) and continue weekly from there
Reported response rates to this protocol are excellent, with 59% to 76% of cats achieving complete clinical remission, reported median survival times ranging from 20 to 30 months for those cats responding to therapy, and reports of individual cats surviving as long as 76 months.43, 73, 84 The original reported protocol comprised prednisolone (10 mg/cat, PO or 2 mg/kg, PO) given daily with chlorambucil pulsed by administration of 15 mg/m 2 for 4 days every 3 weeks
