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High minimums

However, hepatic concentrations of AQ and DEAQ are likely higher as AQ strongly accumulates in the liver ( in vivo may be lower, exposure continues for a prolonged period as the half-life of DEAQ is 10 to 12 days (Krishna and White, 1996

GHK-Cu is present in various human biological fluids, including plasma, saliva, and urine

F1000Research 4 , 1521 (2016)

However, urine output is not a very reliable index in patients who are taking medication or are perioperative, and other commonly used surrogate indices, such as the serum creatinine concentration, creatinine clearance, or GFR, can only show that AKI and functional impairment is already present, rather than being predictors of their development at an early stage (113)

2018;9:2651 Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, et al