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If it looks cloudy, milky, or has changed color (such as turning slightly yellow or brown), do not use it

B12 is virtually non-toxic and, for most people, the shots are nearly painless

Cochrane is the highest level of medical evidence when it comes to comparing treatment options

*Correspondence: Xue Li, [email protected] This article was submitted to Inflammation, a section of the journal Frontiers in Immunology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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