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Like bardoxolone and Omaveloxolone, oltipraz enhances the expression of antioxidant and phase II detoxification enzymes [171]

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This provides an interface by which immune cells, even from distant sites, can gain local access to pancreatic islets ( The dense islet vasculature network facilitates activated immune cell trafficking across the vascular endothelium into the islet ( Figure 1 )

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