Tabe Y, Sekihara K, Yang H, Saito K, Ruvolo V, Taka H, Kaga N, Miida T, Andreeff M , Spagnuolo PA, Konopleva M
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What forms the bulk of the retail price2 of peptides is not the cost of manufacturing, but the capital infrastructure: the regulatory burden, the cold chain logistics, the pen device (which sometimes costs more than the drug itself), and, above all, the return needed to justify $9 billion in the initial R&D of these GLP-1 drugs
Meta-analysis of variation: ecological and evolutionary applications and beyond
Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia