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The findings of this review indicate that GLP-1 receptor agonists exert promising direct neuroprotective properties by targeting multiple components of the ischemic cascades triggered after stroke that contribute to infarct consolidation and poor functional outcome. The group added that they also identified reductions in oxidative stress, cell death markers and inflammatory mediators in multiple studies, but these observations are largely associated and do not establish causality. Of course, none of these trials included human subjects

The way we counter that is by doing a series of microneedling, instead of just 1 treatment, and/or augmenting it with other treatment modalities, including a few options that can boost the results from each single treatment

Fan L, Wang T, Chang L, Song Y, Wu Y, Ma D

Toxicology 5-20-2007;234(3):145-156

The hidden impact of GLP 1 receptor agonists on endometrial receptivity and implantation

Patients who already supplement B12 orally are unlikely to benefit further from injectable B12