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Cell 135 , 12011212 (2008)

The solution is now ready for dosing

Hydroxocobalamin is widely recommended for the treatment of diagnosed B12 deficiency, pernicious anaemia, fatigue related to low B12, and certain neurological symptoms associated with deficiency

This was found to occur because the antibody attaches in an area of the enzyme that usually captures calcium, which is required for enzymatic activation, but binds much more strongly

If there is enough B12 at work in the cells, it keeps these two substances down, and the results of these tests will be low