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Glyoxalase II (EC 3.1.2.6) catalyzes the hydrolysis of S -D-lactoylglutathione to glutathione and D-lactic acid

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MS is the leading cause of disability among young adults and has a large economic burden

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Blocking lipid peroxidation also increased complex I and II activity and the overall efficiency of ETC coupling to ATP synthesis (as measured by the ratio of State III/IV O 2 consumption: RCR)