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Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center

Tumor necrosis factor-alpha inhibits seizures in mice via p75 receptors

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The 1:1 reflects equal mechanistic emphasis

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Overall diet and hydration: Glutathione works as part of a larger system not in isolation