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In contrast, a meta-analysis by Silverii et al

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Advanced techniques like cryoelectron microscopy, X-ray scattering, and hydrogen-deuterium exchange have elucidated the structure of the ligand-bound VDR/RXR complex, providing insights into VDR-coactivator interactions and enabling cell- and gene-specific clinical applications [14,17]

Tirzepatide is the stronger option for patients who have plateaued on semaglutide or who need more aggressive weight loss