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10.1123/japa.14.1.59 168 LandriganJ

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Previous studies identified that mutation of Y211 to phenylalanine resulted in reduced carnitine transport whereas the transport of the cationic probe compound tetraethylammonium was unaffected 16 , indicating that Y211, through its hydroxyl moiety, plays a role in recognising the carboxyl of carnitine

Histologically, a thin layer of parakeratosis with positive signals for EBV is found [22]

Exposure to toxins such as cigarette smoke, air pollution, and heavy metals can also deplete glutathione levels

This effect is most pronounced during early treatment and may diminish with continued therapy