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Furthermore, recent studies suggested that GSH oral administration in liposomal or sublingual forms may have a better bioavailability, with a favorable impact on systemic GSH levels (29, 30)

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GSH activity is facilitated by activation of the Kelch-like ECH-associated protein 1 (Keap1)-Nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) redox regulator pathway, releasing Nrf2 that regulates expression of genes controlling antioxidant, inflammatory and immune system responses

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Some people may experience mild bloating or digestive upset when starting a new supplement, so it is often best to take it with a small amount of water or follow the dosage instructions on the label