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Does elevated vitamin B12 always point to an underlying medical condition

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Providers routinely encounter patients who experience severe gastrointestinal intolerance, metabolic adaptation, or frustrating weight loss plateaus that render these first-line therapies insufficient

In the phase 2 trial of cagrilintide 2.4 mg co-administered with semaglutide 2.4 mg (CagriSema) in people with type 2 diabetes, the combination improved glycemic control and body weight relative to semaglutide alone, consistent with amylin adding a postprandial glucose-lowering contribution on top of GLP-1 action