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doi: 10.1038/srep29743 (2016)

While FOXO4 can influence mitochondrial function indirectly through its regulatory effects on cellular processes, it does not directly target mitochondria like the other mitochondria-targeted peptides listed above

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Research on the closely related GHK-Cu demonstrates improved collagen production in treated skin compared to various controls including vitamin C cream and retinoic acid

Unfortunately, the location of biotin incorporation and to a lesser extent, the number of added biotins per molecule cannot be well-controlled

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