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MS: Conceptualization, Supervision, Writing review & editing

Acknowledgments The authors would like to express their gratitude to the Experimental Animal Center and Core Facility Center at Tzu Chi University for their invaluable assistance with animal care, confocal microscopy, and flow cytometry experiments

At 32 weeks, the reduction in HbA1c levels with CagriSema was statistically superior to cagrilintide alone, but not statistically greater than semaglutide 6

Antioxidant defense : NADH can donate electrons to neutralize free radicals, protecting cells from oxidative damage

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