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Angiotensin AT4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP)

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A number of clinical studies established that GHK-CU stimulates the synthesis of collagen, the production of selected glycosaminoglycans (like hyaluronic acid), and modulates matrix metalloproteinases (MMPs)

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Funding The authors gratefully acknowledge use of the services and facilities of the Ko University Research Center for Translational Medicine (KUTTAM), funded by the Republic of Turkey Ministry of Development