doi: 10.1172/JCI200318182
With 11% of U.S

Here's a selection of medications our physicians may recommend: Semaglutide (Wegovy, Ozempic) GLP-1 receptor agonist Administered as an injection weekly Side effects include gastrointestinal symptoms, headache, dizziness, and fatigue Tirzepatide (Zepbound, Mounjaro) It is both a GLP-1 and a GIP receptor agonist Also administered as an injection weekly Works by reducing appetite Liraglutide (Saxenda) - Delivered to your pharmacy, paid by you (10-100$ monthly or covered by insurance) Daily injectable medication to reduce hunger signals Side effects include nausea, diarrhea, increased lipase, and renal insufficiency Phentermine (Adipex, Suprenza) - Delivered to your pharmacy, paid by you (10-100$ monthly or covered by insurance) Phentermine is the oldest and most widely used weight loss medication Side effects include headache, high blood pressure, and insomnia, rapid or irregular heart rate, and tremor Phentermine-topiramate (Qsymia) - Delivered to your pharmacy, paid by you (10-100$ monthly or covered by insurance) Topiramate can be combined with phentermine to decrease appetite and cravings

Most patients experience mild appetite return but retain 7080% of their previous dose's benefit
It means appetite suppression and nutritional adequacy are not the same thing
On an aggregated basis, it costs between $200 and $600 a month, depending on your pharmacy and dosage