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CS is the primary cause of chronic obstructive pulmonary disease (COPD), with as much as 90% of COPD patients having been smokers at one point in their lifetime [5, 6]

doi: 10.1016/j.semcdb.2011.05.005, PMID: [DOI] [PubMed] [Google Scholar] 16.Cui T, Terlecki R

Diabetes-associated sustained activation of the transcription factor nuclear factor-B

Side effects are generally mild and may include temporary redness at the injection site, headache, or nausea

In addition to its systemic metabolic advantages, metformin can penetrate the blood-brain barrier (BBB) and has shown promise in improving cognitive function

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