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[7] PharmaCotherapia d.o.o., Phase I, Pilot Study in Healthy Volunteers, to Assess the Safety and Pharmacokinetics of PCO-02, Which Active Ingredient is BPC-157, a Penta-deca-peptide From Gastric Source., clinicaltrials.gov, Clinical trial registration NCT02637284, Dec
The chemical site of action is the reactive thiol group on the cysteine residue
glutamic acid, cysteine, and glycine The synthesis of glutathione in the body involves two enzymes, the first of which binds L-cysteine and glutamic acid to one another in a gamma configuration (producing -glutamylcysteine), and the second enzyme adds a glycine molecule onto it to ultimately form glutathione
Normal rabbit IgG (#I8410, Sigma) was used as a non-specific antibody control