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Nasal sprays are classified as Orally Inhaled and Nasal Drug Products (OINDPs) under FDA regulatory nomenclature and are subject to highly specific testing requirements that extend far beyond the generic pharmaceutical testing categories

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For cell maintenance the serum concentration was lowered to 2% (maintenance MEM)

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Typical doses range from 90200 mg daily for general supplementation, though higher doses have been studied for specific conditions

Ultrathin sections (80 nm thick) were cut with an ultramicrotome (Leica, EMUC6, Germany), and then stained with uranyl acetate and lead citrate and finally examined by a Tecnai G 2 Spirit TWIN transmission electron microscope (FEI, Hillsboro, OR, USA)