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Schep LJ et al (2009): Nicotinic plant poisoning

In real-world observations, individuals on GLP-1 therapies often fall below dietary benchmarks for: 3,5 Microminerals : magnesium, potassium, calcium, iron, and zinc Vitamins : D, A, E, K, B12, B1 (thiamine), and folate Macronutrients : protein and fiber Phytonutrients : including carotenoids and flavonoids Gastrointestinal effectsincluding nausea, bloating, early satiety, and evolving food aversionsfurther constrict intake variety and volume, amplifying the risk

Rossi and colleagues, review, Acta Diabetologica , 2025)

3-PH can obtain an amino group from glutamate and form 3-phosphoserine (3-PS) through phosphoserine transaminase (PSAT) followed by dephosphorylation through serine phosphatase (PSPH) to finally produce serine (Figure 1)

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Against the 2.4 mg weight-management dose, the difference is smaller