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Description

The 26% MACE reduction in SUSTAIN-6, the 20% reduction in SELECT, and the 42% reduction in atrial fibrillation risk from meta-analysis data paint a picture of a medication that protects the heart far more than it burdens it

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This phenomenon is independent of DPP-IV, the GLP-1 receptor, or the PYY related peptide NPY

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It is important to note that current in vitro redox cycling detection is centred on indirect quantification of H 2 O 2 production and O 2 consumption rather than direct measurement of dynamic radical species over time 22,28

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