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Finan B, Yang B, Ottaway N et al (2015) A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents

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On top of which, one group was fed a methyl rich diet, and the other group, a normal mouse diet

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Standard cycle: 46 weeks Extended cycle with monitoring: up to 12 weeks for complex or chronic presentations Rest period between cycles: 48 weeks is typical Duration matters because tissue remodeling continues for weeks after a cycle ends