Age, sex and post-mortem interval were included as covariates, and controlled for in the regression analysis
The across time measures of LAC were taken at rest as well as four and fourteen minutes post exercise while thigh girth was assessed at rest and four minutes after the fifth sprint
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Mass spectrometry confirmation of correct molecular weight adds further verification
Most importantly, they demonstrate efficacy against schistosome infections in mice, meeting the criteria for lead progression indicated by WHO, and outperform the previously reported efficacy of praziquantel against juvenile worms 13