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There is a tremendous range of possible presentations, with local and remote effects which wax and wane over time
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(2020) Betaine and choline status modify the effect of folic acid and creatine supplementation on arsenic methylation in a randomised controlled trial of Bangladeshi adults, Eur J Nutr, vol
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Its defining physicochemical feature is resistance to hydrolysis at low pH, unusual for a peptide of this length and attributed to a proline-rich, conformationally constrained backbone carrying three consecutive prolines plus a fourth at position eight
