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Alfenito et al, 1998), and naturally occurring endogenous reactive electrophilic compounds (Marrs, 1996), but may have then been recruited to detoxify anthropogenic exogenous xenobiotics (Kreuz et al, 1996

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Quantitative analyses indicate that more than 60% of cytoplasmic copper exists as a GSH-bound complex, positioning GSH as the primary initial copper ligand following cellular uptake 167

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