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Individuals with faster hepatic metabolism (common in those taking enzyme-inducing medications or with genetic polymorphisms affecting CYP enzymes) may experience shorter duration of effects and slightly delayed onset as the peptide is metabolized before reaching peak CNS concentrations

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Seek immediate emergency care if you experience severe abdominal pain that radiates to the back, persistent vomiting preventing fluid intake, signs of allergic reaction (difficulty breathing, facial swelling, severe rash), or symptoms of acute pancreatitis

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