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Studies show that getting only four hours of sleep for a few nights in a row can impair GLP-1 function and increase cravings for sugar and processed foods

Abrahamsen, Rannv K., A

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Moreover, FOXO4-DRI significantly decreased the viability of senescent Leydig cells and dramatically increased their apoptosis rate from 10% to 27%

While some people taking GLP-1 agonists experience difficult side effects, including nausea, vomiting and diarrhoea, and there is a need for more data on the impact of long-term use of these medicines, currently available data suggest that the benefits associated with GLP-1 agonists outweigh their risks