In many cases, plans may also need documentation that the drug is being used alongside a supervised weight-loss program
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Losing weight in this way is immoral without the oversight of an IRB, and no IRB would allow such an obvious conflict of interest, where the subject gains significant health improvements in exchange for participating
Phase 3 trials, which involve larger and more diverse populations over longer durations, are currently underway (see ClinicalTrials.gov for registered studies) and will provide more robust evidence before any regulatory submission can be considered
Sanyal Arun J, Pierre B, Mandy F, Neff Guy W, Eric L, Elisabetta B et al