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doi: 10.1002/pros.23951 211 IwayaCNomiyamaTKomatsuSKawanamiTTsutsumiYHamaguchiYet al

The main outcome was the incidence of hospitalization for heart failure

The observation that the induced effect on insulin secretion is different when oral glucose was administered versus the same amount of glucose parenterally coined the term incretin effect, supporting the idea that some substances secreted in the intestines favored the release of insulin after ingestion [1]

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However, these tests have limitations, including nonspecific readings in the context of polytrauma, limited availability in the acute care setting and minimal mechanistic insight [23, 24]

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