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A 2025 network meta-analysis ranked nausea risk as follows: orforglipron (highest, relative risk 4.77), liraglutide (3.09), semaglutide (2.94), tirzepatide (2.89), exenatide (2.66), and cagrilintide (2.29)

The best results typically come from consistent treatment, follow-up, nutrition changes, and activity planning

The phase 2 study specifically measured cravings and found significant reductions in desire for sweet foods (as early as week 4), salty foods (by week 16), and fatty foods (by weeks 12-16) at doses of 4mg and above compared to placebo

In some cases, hair loss can be indicative of an underlying issue, such as hormone changes or autoimmune problems

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Urbanski said