The sustained nature of these results distinguishes GLP-1 medications from previous weight loss interventions, which typically show significant weight regain over time ^3
Tirzepatide does all of that as a GIP/GLP-1 dual agonist and additionally engages the GIP receptor, adding a second incretin mechanism
Together with other aspects of the PWS phenotype including, in many cases, a reduced sensitivity to pain, hyperphagia results in life-threatening obesity and life-shortening complications for some people with PWS
While tirzepatide itself is not directly responsible for hair loss, the body's physiological response to swift changes in body weight often leads to a condition known as telogen effluvium
Low testosterone is common in patients with obesity and directly impairs the bodys ability to maintain muscle mass during caloric restriction
We desperately need an effective way to treat knee pain. Certain factors that accelerate osteoarthritis, like age and genetic predisposition, are beyond our control, but others, like obesity and exercise, fall within it
