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We found that while the docetaxel decreased the G0/G1 phase, both chlorophyllin and its coadministration with docetaxel led to a slight increase in the G0/G1 phase compared to the control group after 24 h of incubation

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It has been reported that by inhibiting phosphorylation of serine 10 in this pathway, breast cancer cells simultaneously challenged with estradiol show an overproduction of ROS, with increased oxidation of the DNA that overwhelms the repair apparatus and triggers PCD in a great percentage of these cells 144 (Fig