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For patients with CKD, treatment plans are tailored to individual needs to maximize effectiveness while minimizing risks

Participants who experienced significant nausea, vomiting, or other gastrointestinal symptoms during escalation could have their dose increase paused or delayed until symptoms resolved

And at the maximum studied dose of 12 mg, average weight loss hit 24.2% at 48 weeks

Data were pooled using random-effects models, and subgroup analyses were performed by drug type and treatment duration

The FDA based its decision on results from the Researching Cardiovascular Events with a Weekly Incretin in Diabetes (REWIND) trial

For Canadian patients particularly, the conversation around medication dependency carries unique weight given our universal healthcare culture that emphasizes prevention and lifestyle